Protein Modification Reagents
![Medchemexpress LLC L-Prolinamide, N-[2-[3-[4-[3-[4-[[5-bromo-4-[[3-[(cyclobutylcarbonyl)methylamino]propyl]amino]-... | 2052306-13-3 | 98.2% | 1093.18 g/mol | C53H74BrN9O9S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264323.png-250.jpg)
Medchemexpress LLC L-Prolinamide, N-[2-[3-[4-[3-[4-[[5-bromo-4-[[3-[(cyclobutylcarbonyl)methylamino]propyl]amino]-... | 2052306-13-3 | 98.2% | 1093.18 g/mol | C53H74BrN9O9S | 5 MG
PROTAC TBK1 degrader-2 is a small-molecule PROTAC that binds and induces degradation of TANK-binding kinase 1 (TBK1). It shows potent biochemical and cellular activity and is intended for target validation and mechanism-of-action studies in research settings.
- Potent degradation of TBK1 (DC50 = 15 nM).
- High binding affinity to TBK1 (Kd = 4.6 nM).
- Low-nanomolar inhibitory activity (IC50 TBK1 = 1.3 nM; IKKε = 8.7 nM).
- High reported purity suitable for research (98.2%).
- White to off-white solid with good DMSO solubility (110 mg/mL).
- Intended for cellular and biochemical PROTAC studies and target validation.
Medchemexpress LLC (S,R,S)-AHPC-PEG5-Boc | 2923734-82-9 | 95.3% | C40H62N4O11S | 10MG
(S,R,S)-AHPC-PEG5-Boc is an E3 ligase ligand-linker conjugate that couples an (S,R,S)-AHPC-based VHL ligand to a PEG5 linker with a Boc protecting group. Supplied as a solid research reagent, it is intended for use as the ligand-linker component in PROTACs such as Cdc20-targeting degraders.
- Incorporates the (S,R,S)-AHPC VHL ligand
- Contains a PEG5 linker with Boc protection
- Provided as a solid, light yellow to yellow material
- Molecular formula: C40H62N4O11S
- Molecular weight: 807.01 g·mol⁻¹
- Reported purity: 95.3%
- Storage: -20 °C under nitrogen; in solvent -80 °C (6 months) or -20 °C (1 month)
- Available in milligram to gram sizes for research use
Chemscene ChemScene | Mal-amido-PEG8-NHS ester | 100MG | CS-W020873 | 0.98 | 756525-93-6| MFCD11041144 | 689.71
ChemScene | Mal-amido-PEG8-NHS ester | 100MG | CS-W020873 | 0.98 | 756525-93-6| MFCD11041144 | 689.71
Chemscene ChemScene | Boc-NH-PEG4-CH2CH2COOH | 250MG | CS-W020872 | 0.98 | 756525-91-4| MFCD07781254 | 365.42
ChemScene | Boc-NH-PEG4-CH2CH2COOH | 250MG | CS-W020872 | 0.98 | 756525-91-4| MFCD07781254 | 365.42
ABclonal Technology MYH6/α-MHC Rabbit pAb
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
ABclonal Technology MYH6/α-MHC Rabbit pAb
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
ABclonal Technology TLX1 Rabbit pAb
This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
ABclonal Technology TLX1 Rabbit pAb
This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.